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Article

Osteopontin contributes to late-onset asthma phenotypes in adult asthma patients.

Experimental & molecular medicine - 1 Feb 2020

Trinh Hoang Kim Tu, Nguyen Thuy Van Thao, Kim Seo-Hee, Cao Thi Bich Tra, Luu Quoc Quang, Kim Seung-Hyun, Park Hae-Sim

Abstract excerpt

Patients with late-onset asthma (LOA) have poor clinical outcomes. Osteopontin (OPN) is associated with airway inflammation and remodeling. To investigate the role of OPN in LOA compared to early-onset asthma (EOA), serum OPN levels were compared between 131 adult asthma patients (48 LOA and 83 EOA patients) and 226 healthy controls (HCs). BALB/c mice were sensitized with ovalbumin with/without...

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Identifiers

PMID: 32009132
DOI: 10.1038/s12276-020-0376-2
PMCID: PMC7062758

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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