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Article

Novel Quinolone Nonsusceptible Streptococcus canis Strains with Point Mutations in Quinolone Resistance-Determining Regions and Their Related Factors.

Japanese journal of infectious diseases - 22 May 2020

Fukushima Yasuto, Tsuyuki Yuzo, Goto Mieko, Yoshida Haruno, Takahashi Takashi

Abstract excerpt

This study investigated quinolone nonsusceptible Streptococcus canis with point mutations in quinolone resistance-determining regions (QRDRs). After selecting targets from 185 isolates, we tested antimicrobial susceptibility using levofloxacin, ciprofloxacin, norfloxacin, and moxifloxacin. We also determined the amino acid sequences of QRDRs in gyrA/gyrB/parC/parE genes and their point mutations. Finally, we...

Topics

Alleles
Animals
Anti-Bacterial Agents
Bacterial Proteins
Dogs
Drug Resistance, Bacterial
Female
Genotype
Male
Microbial Sensitivity Tests
Point Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Quinolones

Sequence Analysis, DNA

Streptococcal Infections

Streptococcus

Source

Identifiers

PMID: 32009056
DOI: 10.7883/yoken.JJID.2019.392

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-32009056-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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