Article
Correlation of plasma butyrylcholinesterase concentration with Acethylcholinesterase H353N polymorphism in the inflammatory response of Chagas disease patients.
Parasitology international - 1 Jun 2020
Campello A C, Zanella L G F A B D E, Suzuki R B, Tokumo M O, Chagas E F B, Baleotti W, Sperança M A, Martins L P A
Abstract excerpt
Trypanosoma cruzi infection triggers an intense production of pro-inflammatory cytokines mediated by T helper 1 lymphocytes, inducing the anti-inflammatory reflex of acetylcholine (ACh). The ACh concentration modulation is associated to the two major esterases, the acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). AChE H353N protein polymorphism is related to low Chagas chronic disease prognostic. In...
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