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Article

Generation and characterization of a cell line from an intraductal tubulopapillary neoplasm of the pancreas.

Laboratory investigation; a journal of technical methods and pathology - 1 Jul 2020

Felsenstein Matthäus, Trujillo Maria A, Huang Bo, Nanda Neha, Jiang Zhengdong, Jeong Yea Ji, Pflüger Michael, Goggins Michael G, Hruban Ralph H, Thompson Elizabeth D, Heaphy Christopher M, Roberts Nicholas J, Wood Laura D

Abstract excerpt

Intraductal tubulopapillary neoplasm (ITPN) is a distinct precancerous lesion in the pancreas with unique clinical and molecular features. Although in vitro studies in two-dimensional culture have led to numerous important insights in pancreatic cancer, such models are currently lacking for precancerous lesions. In this study, we report the generation and characterization of a cell line from a human pancreatic...

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PMID: 32005909
DOI: 10.1038/s41374-020-0372-0
PMCID: PMC7316603

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