Article
Keratinocyte aquaporin-3 expression induced by histone deacetylase inhibitors is mediated in part by peroxisome proliferator-activated receptors (PPARs).
Experimental dermatology - 1 Apr 2020
Yang Rong, Chowdhury Shinjini, Choudhary Vivek, Chen Xunsheng, Bollag Wendy B
Abstract excerpt
The water and glycerol channel, aquaporin-3 (AQP3), plays an important role in the skin epidermis, with effects on hydration, permeability barrier repair and wound healing; therefore, information about the mechanisms regulating its expression is important for a complete understanding of skin function physiologically and in disease conditions. We previously demonstrated that histone deacetylase inhibitors (HDACi)...
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