Article
MicroRNA-206: A Potential Circulating Biomarker Candidate for Amyotrophic Lateral Sclerosis
20 Feb 2014
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease that progressively debilitates neuronal cells that control voluntary muscle activity. Biomarkers are urgently needed to facilitate ALS diagnosis and prognosis, and as indicators of therapeutic response in clinical trials. microRNAs (miRNAs), small posttranscriptional modifiers of gene expression, are frequently altered in disease conditions....
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