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Article

Signature tau neuropathology in gray and white matter of corticobasal degeneration.

The American journal of pathology - 1 Jun 2002

Forman Mark S, Zhukareva Victoria, Bergeron Catherine, Chin Steven S-M, Grossman Murray, Clark Chris, Lee Virginia M-Y, Trojanowski John Q

Abstract excerpt

Corticobasal degeneration (CBD) is an adult-onset progressive neurodegenerative disorder characterized by L-dopa-resistant rigidity, focal cortical deficits, and variable dementia. The neuropathological hallmark of CBD is the deposition of filamentous inclusions in neurons and glia composed of hyperphosphorylated tau with only four microtubule-binding repeats (4R-tau). To characterize the regional burden of tau...

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Identifiers

PMID: 12057909
DOI: 10.1016/S0002-9440(10)61154-6
PMCID: PMC1850831

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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