Article
STAT1 is a key gene in a gene regulatory network related to immune phenotypes in bladder cancer: An integrative analysis of multi-omics data.
Journal of cellular and molecular medicine - 1 Apr 2021
Weng Hong, Yuan Shuai, Huang Qiao, Zeng Xian-Tao, Wang Xing-Huan
Abstract excerpt
The immunophenotype of bladder cancer plays a pivotal role in the prognosis of cancer, but the effect of different epigenetic factors on different immunophenotypes in bladder tumours remains unclear. This study used multi-omics data analysis to provide molecular basis support for different immune phenotypes. Unsupervised cluster analysis revealed distinct subclusters with higher (subcluster B2) or lower cytotoxic...
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