Article
Genetic and nutritional factors determining circulating levels of lipoprotein(a): results of the "Montignoso Study".
Internal and emergency medicine - 1 Oct 2020
Sereni Alice, Sticchi Elena, Gori Anna Maria, Magi Alberto, Della Latta Daniele, Volta Andrea, Murri Alessandra, Jamagidze Giuli, Chiappino Dante, Abbate Rosanna, Gensini Gian Franco, Marcucci Rossella, Sofi Francesco, Giusti Betti
Abstract excerpt
Increasing evidence shows an association between high lipoprotein(a) [Lp(a)] levels and atherothrombotic diseases. Lp(a) trait is largely controlled by kringle-IV type 2 (KIV-2) size polymorphism in LPA gene, encoding for apo(a). Environmental factors are considered to determinate minor phenotypic variability in Lp(a) levels. In the present study, we investigated the possible gene-environment interaction between...
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