Article
Association between SNPs and Loss of Methylation Site on the CpG island of the Promoter Region of the Smoothened Gene, Potential Molecular Markers for Susceptibility to the Development of Basal Cell Carcinoma in the Brazilian Population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2020
Souza Augusto Monteiro de, Lopes Otávio Sérgio, Liberato Andressa de Lima, Oliveira Paulo Junior Ribeiro de, Herrero Sylvia Satomi Takeno, Nascimento Agnaldo Luiz do, Longui Carlos Alberto, Carvalho Filho Ivan Rodrigues de, Soares Leonardo Ferreira, Silva Renally Barbosa da, Burbano Rommel Rodriguez, Delatorre Plínio, Lima Eleonidas Moura
Abstract excerpt
OBJECTIVE: Perform genotyping of SNPs in the promoter region of the SMO gene in BCC samples from patients from northeastern Brazil, and to determine if there is an association of these SNPs of the gene in question with the susceptibility to the development of the BCC. METHODS: 100 samples of paraffined tissue from patients with histopathological diagnosis of BCC and 100 control samples were analyzed for each...
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