Article
Association of the genetic variants (-794 CATT5-8 and -173 G > C) of macrophage migration inhibitory factor (MIF) with higher soluble levels of MIF and TNFα in women with breast cancer.
Journal of clinical laboratory analysis - 1 May 2020
Avalos-Navarro Guadalupe, Del Toro-Arreola Alicia, Daneri-Navarro Adrián, Quintero-Ramos Antonio, Bautista-Herrera Luis Alberto, Franco Topete Ramon Antonio, Anaya Macias Brian Uriel, Javalera Castro David Israel, Morán-Mendoza Andrés de Jesús, Oceguera-Villanueva Antonio, Topete-Camacho Antonio, Muñoz-Valle José Francisco
Abstract excerpt
BACKGROUND: Functional variants -173 G > C (rs755622) and -794CATT5-8 (rs5844572) MIF gene have been associated with the risk in several types of cancer, as well as with the increase of soluble levels of MIF and TNFα. However, in previous studies contradictory and uncertain results have been presented on the implication of MIF polymorphisms with the association in cancer, specifically in breast cancer (BC). We...
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