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The clinical signature of genetic variants and serum levels of macrophage migration inhibitory factor in Egyptian breast cancer patients.

Breast cancer research and treatment - 1 Nov 2024

Seliem Mahmoud A, Mohamadin Ahmed M, El-Sayed Mohamed I Kotb, Ismail Yahia, El-Husseiny Ahmed A

Abstract excerpt

PURPOSE: Macrophage migration inhibitory factor (MIF) is an integral cytokine for the modulation of both innate and adaptive immunity and is involved in the pathogenesis of various cancers. However, conflicting findings on the relationship between MIF polymorphisms and breast cancer (BC) have been reported in earlier research. We investigated the clinical value of serum MIF levels and the association between MIF...

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Identifiers

PMID: 38916819
DOI: 10.1007/s10549-024-07393-9
PMCID: PMC11452551

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