Article
Significant association between methylenetetrahydrofolate reductase gene C677T polymorphism with polycystic ovary syndrome risk: A meta-analysis update.
Medicine - 1 Jan 2020
Li Yin, Zhu Hongqiu, Liu Min, Zeng Zhulan, Zeng Yanling, Xu Xinlei, Ye Min
Abstract excerpt
The methylenetetrahydrofolate reductase (MTHFR) may play a pathological role in polycystic ovary syndrome (PCOS). However, the conclusions of published reports on the relationship between the MTHFR C677T polymorphism and PCOS risk remain controversial.To derive a more precise estimation we performed a metaanalysis based on 22 studies that together included 2405 cases and 2419 controls. PubMed, EMBASE, WanFang and...
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