Article
Treatment outcome and clinical characteristics of HER2 mutated advanced non-small cell lung cancer patients in China.
Thoracic cancer - 1 Mar 2020
Xu Fei, Yang Guangjian, Xu Haiyan, Yang Lu, Qiu Weini, Wang Yan
Abstract excerpt
BACKGROUND: HER2 mutation is found in 1%-2% of lung cancer patients. Studies comparing chemotherapy to HER2-TKIs are limited. This study aimed to investigate the molecular and clinical patterns of HER2 mutations in advanced non-small cell lung cancer (NSCLC), and compare the different outcomes between chemotherapy and HER2-TKIs. METHODS: Advanced or recurrent non-small cell lung cancer patients with de novo HER2...
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