Article
Structural insights into the conformational change of Staphylococcus aureus NreA at C-terminus.
Biotechnology letters - 1 May 2020
Sangare Lancine, Chen Wanbiao, Wang Chengliang, Chen Xiaobao, Wu Minhao, Zhang Xuan, Zang Jianye
Abstract excerpt
Staphylococcus aureus is an anaerobic facultative microorganism that features the NreABC system for nitrate respiration. NreB is the sensor histidine kinase that phosphorylates the response regulator NreC to stimulate the expression of target genes. NreA is a nitrate sensor which dissociates from NreB in the present of nitrate and relieves its inhibition on NreB. However, the molecular basis of how NreA regulate...
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