Article
Vitamin D-related genes and cardiometabolic markers in healthy children: a Mendelian randomisation study.
The British journal of nutrition - 28 May 2020
Lopez-Mayorga Ania, Hauger Hanne, Petersen Rikke A, Vogel Ulla, Damsgaard Camilla T, Lauritzen Lotte
Abstract excerpt
Observational studies show associations between low serum 25-hydroxyvitamin D (25(OH)D) and cardiometabolic risk markers. This Mendelian randomisation study examined associations between cardiometabolic markers in children and SNP in genes related to vitamin D metabolism (DHCR7; group-specific complement (GC); cytochrome P450 subfamily IIR1 (CYP2R1); and CYP24A1) and action (CYP27B1 and VDR). In 699 healthy...
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