Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal VDR variants rather than 25-hydroxyvitamin D concentration during early pregnancy are associated with type 1 diabetes in the offspring.

Diabetologia - 1 Oct 2015

Miettinen Maija E, Smart Melissa C, Kinnunen Leena, Mathews Christopher, Harjutsalo Valma, Surcel Heljä-Marja, Lamberg-Allardt Christel, Tuomilehto Jaakko, Hitman Graham A

Abstract excerpt

AIMS/HYPOTHESIS: We investigated whether single nucleotide polymorphisms (SNPs) associated with 25-hydroxyvitamin D concentration in the metabolic pathway of vitamin D show different genotype distributions between Finnish families with an offspring with type 1 diabetes (cases) and families with a healthy offspring (controls). METHODS: A total of 31 SNPs in eight genes were studied in case and control mothers and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Infant

Share to Infant, Newborn

Share to Pregnancy

Share to Receptors, Calcitriol

Share to Vitamin D

Source

Identifiers

PMID: 26109216
DOI: 10.1007/s00125-015-3675-8

Genes

VDR
DHCR7
NADSYN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal VDR variants rather than 25-hydroxyvitamin D concentration during early pregnancy are associated with type 1 diabetes in the offspring.PMID 26109216Read ↗

Genetic determinants of serum 25-hydroxyvitamin D concentration during pregnancy and type 1 diabetes in the child.Semantic proximity Read ↗

CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans.Semantic proximity Read ↗

Inherited Variation in Vitamin D Genes and Type 1 Diabetes PredispositionSemantic proximity Read ↗

No association between type 1 diabetes and genetic variation in vitamin D metabolism genes: a Danish study.Semantic proximity Read ↗

Vitamin D and Type 1 Diabetes Risk: A Systematic Review and Meta-Analysis of Genetic Evidence.Semantic proximity Read ↗

Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes.Semantic proximity Read ↗

Vitamin D Pathway Genetic Variation and Type 1 Diabetes: A Case-Control Association Study.Semantic proximity Read ↗

A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness).Semantic proximity Read ↗

Association between the rs1544410 polymorphism in the vitamin D receptor (VDR) gene and insulin secretion after gestational diabetes mellitus.Semantic proximity Read ↗

Association of vitamin D receptor gene polymorphisms with gestational diabetes mellitus-a case control study in Wuhan, ChinaSemantic proximity Read ↗

Leptin and IGF-1 in Infancy Are Associated With Variants in DHCR7 and CYP2R1 That Relate With Type 1 Diabetes and 25OHD.Semantic proximity Read ↗

Fetal and Maternal Genetic Variants Influencing Neonatal Vitamin D Status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.