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Article

Identification of novel differentially expressed genes in retinas of STZ‐induced long‐term diabetic rats through RNA sequencing

20 Jan 2020

Abstract excerpt

BACKGROUND: The aim of this research was to investigate the retinal transcriptome changes in long-term streptozotocin (STZ)-induced rats' retinas using RNA sequencing (RNA-seq), to explore the molecular mechanisms of diabetic retinopathy (DR), and to identify novel targets for the treatment of DR by comparing the gene expression profile we obtained. METHODS: In this study, 6 healthy male SD rats were randomly...

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PMID: 31958216
DOI: 10.1002/mgg3.1115

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