Article
Combined analysis of whole-exon sequencing and lncRNA sequencing in type 2 diabetes mellitus patients with obesity.
Journal of cellular and molecular medicine - 1 Feb 2020
An Tian, Zhang Jing, Liu Yu-Fei, Wu Yan-Xiang, Lian Juan, Wang Ting-Ye, Hu Yuan-Yuan, Zhu Jia-Jian, Huang Jiangpinghao, Zhao Dan-Dan, Mo Fang-Fang, Gao Si-Hua, Jiang Guang-Jian
Abstract excerpt
This study sought to find more exon mutation sites and lncRNA candidates associated with type 2 diabetes mellitus (T2DM) patients with obesity (O-T2DM). We used O-T2DM patients and healthy individuals to detect mutations in their peripheral blood by whole-exon sequencing. And changes in lncRNA expression caused by mutation sites were studied at the RNA level. Then, we performed GO analysis and KEGG pathway...
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