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Article

Topography elicits distinct phenotypes and functions in human primary and stem cell derived endothelial cells.

Biomaterials - 1 Mar 2020

Arora Seep, Lin Shiming, Cheung Christine, Yim Evelyn K F, Toh Yi-Chin

Abstract excerpt

The effective deployment of arterial (AECs), venous (VECs) and stem cell-derived endothelial cells (PSC-ECs) in clinical applications requires understanding of their distinctive phenotypic and functional characteristics, including their responses to microenvironmental cues. Efforts to mimic the in-vivo vascular basement membrane milieu have led to the design and fabrication of nano- and micro-topographical...

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Identifiers

PMID: 31951971
DOI: 10.1016/j.biomaterials.2019.119747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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