Article
A genome-wide significant association on chromosome 15 for congenital entropion in Swiss White Alpine sheep.
Animal genetics - 1 Mar 2020
Hirter N, Letko A, Häfliger I M, Becker D, Greber D, Drögemüller C
Abstract excerpt
Entropion is a known congenital disorder in sheep presumed to be heritable but no causative genetic variant has been reported. Affected lambs show a variable inward rolling of the lower eyelids leading to blindness in severe cases. In Switzerland, the Swiss White Alpine (SWA) breed showed a significantly higher prevalence for entropion than other breeds. A GWAS using 150 SWA sheep (90 affected lambs and 60...
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