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Article

LncRNA DINOR is a virulence factor and global regulator of stress responses in Candida auris.

Nature microbiology - 1 Jul 2021

Gao Jiaxin, Chow Eve W L, Wang Haitao, Xu Xiaoli, Cai Chunling, Song Yabing, Wang Jianbin, Wang Yue

Abstract excerpt

The emergent fungal pathogen Candida auris exhibits high resistance to antifungal drugs and environmental stresses, impeding treatment and decontamination1-3. The fungal factors mediating this stress tolerance are largely unknown. In the present study, we performed piggyBac, transposon-mediated, genome-wide mutagenesis and genetic screening in C. auris, and identified a mutant that grew constitutively in the...

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PMID: 34083769
DOI: 10.1038/s41564-021-00915-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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