Article
Cell division is antagonized by the activity of peptidoglycan endopeptidases that promote cell elongation.
Molecular microbiology - 1 Dec 2020
Truong Thao T, Vettiger Andrea, Bernhardt Thomas G
Abstract excerpt
A peptidoglycan (PG) cell wall composed of glycans crosslinked by short peptides surrounds most bacteria and protects them against osmotic rupture. In Escherichia coli, cell elongation requires crosslink cleavage by PG endopeptidases to make space for the incorporation of new PG material throughout the cell cylinder. Cell division, on the contrary, requires the localized synthesis and remodeling of new PG at...
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