CagA phosphorylation EPIYA-C motifs and the vacA i genotype in Helicobacter pylori strains of asymptomatic children from a high-risk gastric cancer area in northeastern Brazil.

doi:10.1590/0074-0276140279

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Article

CagA phosphorylation EPIYA-C motifs and the vacA i genotype in Helicobacter pylori strains of asymptomatic children from a high-risk gastric cancer area in northeastern Brazil.

Memorias do Instituto Oswaldo Cruz - 1 Dec 2014

Braga Lucia Libanez Bessa Campelo, Oliveira Maria Aparecida Alves de, Gonçalves Maria Helane Rocha Batista, Chaves Fernando Kennedy, Benigno Tiago Gomes da Silva, Gomes Adriana Dias, Silva Cícero Igor Simões Moura, Anacleto Charles, Batista Sérgio de Assis, Queiroz Dulciene Maria Magalhães

Abstract excerpt

Helicobacter pylori infection is one of the most common infections worldwide and is associated with gastric diseases. Virulence factors such as VacA and CagA have been shown to increase the risk of these diseases. Studies have suggested a causal role of CagA EPIYA-C in gastric carcinogenesis and...

Topics

Adolescent
Alleles
Amino Acid Motifs
Antigens, Bacterial
Asymptomatic Infections
Bacterial Proteins
Brazil
Child
Early Detection of Cancer
Endemic Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Female

Genotype

Helicobacter Infections

Helicobacter pylori

Humans

Male

Phosphorylation

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25494468
DOI: 10.1590/0074-0276140279
PMCID: PMC4325609

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25494468-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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