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Article

Cascading After Peridiagnostic Cancer Genetic Testing: An Alternative to Population-Based Screening.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 May 2020

Offit Kenneth, Tkachuk Kaitlyn A, Stadler Zsofia K, Walsh Michael F, Diaz-Zabala Hector, Levin Jeffrey D, Steinsnyder Zoe, Ravichandran Vignesh, Sharaf Ravi N, Frey Melissa K, Lipkin Steven M, Robson Mark E, Hamilton Jada G, Vijai Joseph, Mukherjee Semanti

Abstract excerpt

PURPOSE: Despite advances in DNA sequencing technology and expanded medical guidelines, the vast majority of individuals carrying pathogenic variants of common cancer susceptibility genes have yet to be identified. An alternative to population-wide genetic screening of healthy individuals would exploit the trend for genetic testing at the time of cancer diagnosis to guide therapy and prevention, combined with...

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Identifiers

PMID: 31922925
DOI: 10.1200/JCO.19.02010
PMCID: PMC7193752

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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