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Article

Interferon-Independent Innate Responses to Cytomegalovirus

11 Dec 2019

Abstract excerpt

The critical role of interferons (IFNs) in mediating the innate immune response to cytomegalovirus (CMV) infection is well established. However, in recent years the functional importance of the IFN-independent antiviral response has become clearer. IFN-independent, IFN regulatory factor 3 (IRF3)-dependent interferon-stimulated gene (ISG) regulation in the context of CMV infection was first documented 20 years...

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PMID: 31921100
DOI: 10.3389/fimmu.2019.02751

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