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Article

A network analysis revealed the essential and common downstream proteins related to inguinal hernia.

PloS one - 1 Jan 2020

Mao Yimin, Chen Le, Li Jianghua, Shangguan Anna Junjie, Kujawa Stacy, Zhao Hong

Abstract excerpt

Although more than 1 in 4 men develop symptomatic inguinal hernia during their lifetime, the molecular mechanism behind inguinal hernia remains unknown. Here, we explored the protein-protein interaction network built on known inguinal hernia-causative genes to identify essential and common downstream proteins for inguinal hernia formation. We discovered that PIK3R1, PTPN11, TGFBR1, CDC42, SOS1, and KRAS were the...

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Identifiers

PMID: 31910207
DOI: 10.1371/journal.pone.0226885
PMCID: PMC6946160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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