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The antibody response induced FMDV vaccines in sheep correlates with early transcriptomic responses in blood

3 Jan 2020

Abstract excerpt

Foot and mouth disease (FMD) is a highly contagious viral disease with high economic impact, representing a major threat for cloven-hooved mammals worldwide. Vaccines based on adjuvanted inactivated virus (iFMDV) induce effective protective immunity implicating antibody (Ab) responses. To reduce the biosafety constraints of the manufacturing process, a non-replicative human adenovirus type 5 vector encoding FMDV...

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PMID: 31908850
DOI: 10.1038/s41541-019-0151-3

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