Article
From exploring cancer and virus targets to discovering active peptides through mRNA display.
Pharmacology & therapeutics - 1 Dec 2023
Brango-Vanegas José, Leite Michel Lopes, de Oliveira Kamila Botelho Sampaio, da Cunha Nicolau Brito, Franco Octávio Luiz
Abstract excerpt
During carcinogenesis, neoplastic cells accumulate mutations in genes important for cellular homeostasis, producing defective proteins. Viral infections occur when viral capsid proteins bind to the host cell receptor, allowing the virus to enter the cells. In both cases, proteins play important roles in cancer development and viral infection, so these targets can be exploited to develop alternative treatments....
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