Article
Discriminating Bacterial Phenotypes at the Population and Single-Cell Level: A Comparison of Flow Cytometry and Raman Spectroscopy Fingerprinting.
Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Jul 2020
García-Timermans Cristina, Rubbens Peter, Heyse Jasmine, Kerckhof Frederiek-Maarten, Props Ruben, Skirtach Andre G, Waegeman Willem, Boon Nico
Abstract excerpt
Investigating phenotypic heterogeneity can help to better understand and manage microbial communities. However, characterizing phenotypic heterogeneity remains a challenge, as there is no standardized analysis framework. Several optical tools are available, such as flow cytometry and Raman spectroscopy, which describe optical properties of the individual cell. In this work, we compare Raman spectroscopy and flow...
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