Article
Origin and analysis of microbial population heterogeneity in bioprocesses.
Current opinion in biotechnology - 1 Feb 2010
Müller Susann, Harms Hauke, Bley Thomas
Abstract excerpt
Heterogeneity of industrial production cultures is accepted to a certain degree; however, the underlying mechanisms are seldom perceived or included in the development of new bioprocess control strategies. Population heterogeneity and its basics, perceptible in the diverse proficiency of cells, begins with asymmetric birth and is found to recess during the life cycle. Since inefficient subpopulations have...
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