Article
New Advances in Cell Microarray Technology to Expand Applications in Target Deconvolution and Off-Target Screening
30 Dec 2019
Abstract excerpt
Identifying the cell surface receptors of natural ligands, and deconvoluting the receptor targets of candidate drug leads, presents a challenge in medical research and drug discovery. Traditionally, success rates have been low, and screening efforts often generate numerous false-positive hits that require extensive follow-up to either validate or disregard. If successful, receptor identification enables the...
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