Article
Microarrays of cells expressing defined cDNAs.
Nature - 3 May 2001
Ziauddin J, Sabatini D M
Abstract excerpt
Genome and expressed sequence tag projects are rapidly cataloguing and cloning the genes of higher organisms, including humans. An emerging challenge is to rapidly uncover the functions of genes and to identify gene products with desired properties. We have developed a microarray-driven gene expression system for the functional analysis of many gene products in parallel. Mammalian cells are cultured on a glass...
Topics
- Animals
- Cell Line
- Cells, Cultured
- Cloning, Molecular
- DNA, Complementary
- Genes
- MAP Kinase Signaling System
- Oligonucleotide Array Sequence Analysis
- Phenotype
- Plasmids
- Protein Binding
- Proteins
- Tacrolimus Binding Protein 1A
- Transfection
