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On ATG4B as Drug Target for Treatment of Solid Tumours—The Knowns and the Unknowns

24 Dec 2019

Abstract excerpt

Autophagy is an evolutionary conserved stress survival pathway that has been shown to play an important role in the initiation, progression, and metastasis of multiple cancers; however, little progress has been made to date in translation of basic research to clinical application. This is partially due to an incomplete understanding of the role of autophagy in the different stages of cancer, and also to an...

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PMID: 31878323
DOI: 10.3390/cells9010053

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