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Article

Clinical Applications of Autophagy Proteins in Cancer: From Potential Targets to Biomarkers

11 Jul 2017

Abstract excerpt

Autophagy, a lysosome-mediated intracellular degradation and recycling pathway, plays multiple context-dependent roles in tumorigenesis and treatment resistance. Encouraging results from various preclinical studies have led to the initiation of numerous clinical trials with the intention of targeting autophagy in various cancers. Accumulating knowledge of the particular mechanisms and players involved in...

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PMID: 28696368
DOI: 10.3390/ijms18071496

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