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Article

A systematic bioinformatics approach for selection of target and screening of ligand for malignant tumours suppressing APG4A gene on Xq22.1.

International journal of computational biology and drug design - 1 Jan 2010

Niranjan Vidya, Seenivasagam R, Sivakumar G

Abstract excerpt

Autophagy is a biological process involved in the intracellular destruction of endogenous proteins and has been suggested to be essential for cell homeostasis as well as for cell remodelling. Autophagy selectively eradicates damaged cytoplasmic components like injured mitochondria, which increases mutation rates and promote tumour initiation and progression. In addition, autophagy inhibits necrosis, which...

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Identifiers

PMID: 21297227
DOI: 10.1504/IJCBDD.2010.038392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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