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Article

Structural Insights Into PfARO and Characterization of its Interaction With PfAIP.

Journal of molecular biology - 14 Feb 2020

Geiger Michael, Brown Chris, Wichers Jan Stephan, Strauss Jan, Lill Andrés, Thuenauer Roland, Liffner Benjamin, Wilcke Louisa, Lemcke Sarah, Heincke Dorothee, Pazicky Samuel, Bachmann Anna, Löw Christian, Wilson Danny William, Filarsky Michael, Burda Paul-Christian, Zhang Kun, Junop Murray, Gilberger Tim Wolf

Abstract excerpt

Apicomplexan parasites contain rhoptries, which are specialized secretory organelles that coordinate host cell invasion. During the process of invasion, rhoptries secrete their contents to facilitate interaction with, and entry into, the host cell. Here, we report the crystal structure of the rhoptry protein Armadillo Repeats-Only (ARO) from the human malaria parasite, Plasmodium falciparum (PfARO). The structure...

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Identifiers

PMID: 31877322
DOI: 10.1016/j.jmb.2019.12.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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