Article
Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite.
Traffic (Copenhagen, Denmark) - 1 Oct 2012
Cabrera Ana, Herrmann Susann, Warszta Dominik, Santos Joana M, John Peter Arun T, Kono Maya, Debrouver Sandra, Jacobs Thomas, Spielmann Tobias, Ungermann Christian, Soldati-Favre Dominique, Gilberger Tim W
Abstract excerpt
Rhoptries are specialized secretory organelles characteristic of single cell organisms belonging to the clade Apicomplexa. These organelles play a key role in the invasion process of host cells by accumulating and subsequently secreting an unknown number of proteins mediating host cell entry. Despite their essential role, little is known about their biogenesis, components and targeting determinants. Here, we...
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