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Article

Characterization of Polymorphisms Associated with Multidrug-Resistant Tuberculosis by Whole Genomic Sequencing: A Preliminary Report from Mexico.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jul 2020

Zenteno-Cuevas Roberto, Fernandez Esdras, Viveros Diana, Madrazo-Moya Carlos Francisco, Cancino-Muñoz Irving, Comas Iñaki, Gonzalez-Covarrubias Vanessa, Barbosa-Amezcua Martín, Cuevas-Cordoba Betzaida

Abstract excerpt

Whole genome sequencing (WGS) has been proposed as a tool for the diagnosis of drug resistance in tuberculosis (TB); however, there have been few studies on its effectiveness in countries with significantly high drug resistance rates. This study therefore aimed to evaluate the effectiveness of WGS to identify mutations related to drug resistance in TB isolates from an endemic region of Mexico. The results showed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31874045
DOI: 10.1089/mdr.2019.0054

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