Article
Whole genomic sequencing based genotyping reveals a specific X3 sublineage restricted to Mexico and related with multidrug resistance.
Scientific reports - 21 Jan 2021
Jiménez-Ruano Ana Cristina, Madrazo-Moya Carlos Francisco, Cancino-Muñoz Irving, Mejía-Ponce Paulina M, Licona-Cassani Cuauhtémoc, Comas Iñaki, Muñiz-Salazar Raquel, Zenteno-Cuevas Roberto
Abstract excerpt
Whole genome sequencing (WGS) has been shown to be superior to traditional procedures of genotyping in tuberculosis (TB), nevertheless, reports of its use in drug resistant TB (DR-TB) isolates circulating in Mexico, are practically unknown. Considering the above the main of this work was to identify and characterize the lineages and genomic transmission clusters present in 67 DR-TB isolates circulating in...
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