Article
Exploring Bayesian Approaches to eQTL Mapping Through Probabilistic Programming.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2020
Vavoulis Dimitrios V
Abstract excerpt
The discovery of genomic polymorphisms influencing gene expression (also known as expression quantitative trait loci or eQTLs) can be formulated as a sparse Bayesian multivariate/multiple regression problem. An important aspect in the development of such models is the implementation of bespoke inference methodologies, a process which can become quite laborious, when multiple candidate models are being considered....
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