Article
Quantitative trait nucleotide analysis using Bayesian model selection.
Human biology - 1 Oct 2005
Blangero John, Goring Harald H H, Kent Jack W, Williams Jeff T, Peterson Charles P, Almasy Laura, Dyer Thomas D
Abstract excerpt
Although much attention has been given to statistical genetic methods for the initial localization and fine mapping of quantitative trait loci (QTLs), little methodological work has been done to date on the problem of statistically identifying the most likely functional polymorphisms using sequence data. In this paper we provide a general statistical genetic framework, called Bayesian quantitative trait...
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