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Characterization of a live-attenuated HCMV-based vaccine platform

17 Dec 2019

Abstract excerpt

Abstract Vaccines based on cytomegalovirus (CMV) demonstrate protection in animal models of infectious disease and cancer. Vaccine efficacy is associated with the ability of CMV to elicit and indefinitely maintain high frequencies of circulating effector memory T cells (TEM) providing continuous, life-long anti-pathogen immune activity. To allow for the clinical testing of human CMV (HCMV)-based vaccines we...

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Share to Cytomegalovirus and herpesvirus research
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PMID: 31848362
DOI: 10.1038/s41598-019-55508-w

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