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Article

FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1.

Endocrine-related cancer - 1 Mar 2020

Morillo-Bernal Jesús, Fernández Lara P, Santisteban Pilar

Abstract excerpt

FOXE1 is a thyroid-specific transcription factor essential for thyroid gland development and maintenance of the differentiated state. Interestingly, a strong association has been recently described between FOXE1 expression and susceptibility to thyroid cancer, but little is known about the mechanisms underlying FOXE1-induced thyroid tumorigenesis. Here, we used a panel of human thyroid cancer-derived cell lines...

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Share to Cell Line, Tumor
Share to Cell Movement
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forkhead Transcription Factors

Share to Neoplasm Invasiveness

Share to Promoter Regions, Genetic

Share to Thyroid Neoplasms

Share to Zinc Finger E-box-Binding Homeobox 1

Source

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Identifiers

PMID: 31846430
DOI: 10.1530/ERC-19-0156
PMCID: PMC6993207

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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