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Article

Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72

13 Dec 2019

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31843624
DOI: 10.1016/j.brainres.2019.146601

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Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72PMID 31843624Read ↗

Genome-wide synthetic lethal CRISPR screen identifies <i>FIS1</i> as a genetic interactor of ALS-linked <i>C9ORF72</i>Semantic proximity Read ↗

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CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of <i>C9orf72</i> dipeptide repeat protein toxicitySemantic proximity Read ↗

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RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense InterventionSemantic proximity Read ↗

A C9orf72 ALS/FTD Ortholog Acts in Endolysosomal Degradation and Lysosomal HomeostasisSemantic proximity Read ↗

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