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CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity

28 Feb 2018

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29507424
DOI: 10.1038/s41588-018-0070-7

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CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicityPMID 29507424Read ↗

CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of <i>C9orf72</i> dipeptide repeat protein toxicitySemantic proximity Read ↗

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Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72Semantic proximity Read ↗

CRISPR-Cas9 targeted deletion of the <i>C9orf72</i> repeat expansion mutation corrects cellular phenotypes in patient-derived iPS cellsSemantic proximity Read ↗

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