Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention

1 Oct 2013

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Genetic Neurodegenerative Diseases
Share to Neurogenetic and Muscular Disorders Research

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24139042
DOI: 10.1016/j.neuron.2013.10.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense InterventionPMID 24139042Read ↗

Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAsSemantic proximity Read ↗

Antisense Oligonucleotide Therapy for the Treatment of C9ORF72 ALS/FTD DiseasesSemantic proximity Read ↗

RNA-mediated toxicity in C9orf72 ALS and FTDSemantic proximity Read ↗

Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal DeathSemantic proximity Read ↗

Development of Therapeutics for C9ORF72 ALS/FTD-Related DisordersSemantic proximity Read ↗

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72Semantic proximity Read ↗

Engineering Duplex RNAs for Challenging Targets: Recognition of GGGGCC/CCCCGG Repeats at the ALS/FTD C9orf72 LocusSemantic proximity Read ↗

RNA-targeted Therapeutics for ALSSemantic proximity Read ↗

There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS.Semantic proximity Read ↗

ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTDSemantic proximity Read ↗

Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALSSemantic proximity Read ↗

Differential Toxicity of Nuclear RNA Foci versus Dipeptide Repeat Proteins in a Drosophila Model of C9ORF72 FTD/ALSSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.