Article
Correlation between CYP1A1 polymorphisms and susceptibility to glyphosate-induced reduction of serum cholinesterase: A case-control study of a Chinese population.
Pesticide biochemistry and physiology - 1 Jan 2020
Cai Wenyan, Zhang Feng, Zhong Lixin, Chen Dongya, Guo Haoran, Zhang Hengdong, Zhu Baoli, Liu Xin
Abstract excerpt
Glyphosate (GLP) is one of the most common herbicides worldwide. The serum cholinesterase (ChE) may be affected when exposed to glyphosate. Reduction of serum ChE by herbicides is probably related to cytochrome P450 (CYP450) family polymorphisms. We suspect that the abnormal ChE caused by GLP could be correlated with the CYP family members. To determine whether CYP1B1 (rs1056827 and rs1056836) and CYP1A1...
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