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RTX Toxins Ambush Immunity’s First Cellular Responders

10 Dec 2019

Abstract excerpt

The repeats-in-toxin (RTX) family represents a unique class of bacterial exoproteins. The first family members described were toxins from Gram-negative bacterial pathogens; however, additional members included exoproteins with diverse functions. Our review focuses on well-characterized RTX family toxins from Aggregatibacter actinomycetemcomitans (LtxA), Mannheimia haemolytica (LktA), Bordetella pertussis (CyaA),...

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PMID: 31835552
DOI: 10.3390/toxins11120720

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