Article
Tachykinins: Neuropeptides That Are Ancient, Diverse, Widespread and Functionally Pleiotropic
20 Nov 2019
Abstract excerpt
Tachykinins (TKs) are ancient neuropeptides present throughout the bilaterians and are, with some exceptions, characterized by a conserved FXGXRamide carboxy terminus among protostomes and FXGLMamide in deuterostomes. The best-known TK is the vertebrate substance P, which in mammals, together with other TKs, has been implicated in health and disease with important roles in pain, inflammation, cancer, depressive...
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